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Jennie Larkin serves as the Director of the Office of Research Evaluation and Operations (OREO) within the Division of Extramural Activities (DEA) at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health (NIH) (an acronym-rich environment). She provides oversight of the NIDDK's referral and disease coding/reporting functions, and of the program evaluation and analysis capacity. She oversees the NIDDK's Funding Opportunity Announcement (FOA) publication process. Dr. Larkin also provides expertise in data management, sharing policies, and implementation, and participates in trans-NIH committees in this area.

Prior to her work at NIDDK, Dr. Larkin worked as a Senior Advisor in the Extramural Programs and Strategic Planning Office of the Associate Director for Data Science. She chaired the Big Data to Knowledge (BD2K) executive committee and oversaw BD2K extramural programs and strategic planning.

Before joining the NIH Office of Data Science, Dr. Larkin was a Health Scientist Administrator with the Bioengineering and Genomic Applications Scientific Review Group (SRG) in the Division of Heart and Vascular Diseases of the National Heart Lung and Blood Institute (NHLBI), another part of the NIH.

Prior to her work at NHLBI, Dr. Larkin was a staff scientist at The Institute for Genomic Research (TIGR) in Rockville, Maryland, working with Dr. John Quackenbush. Prior to that, Dr. Larkin was a post-doctoral fellow at Stanford University and University of California, Berkeley. At Cal, Dr. Larkin worked with Dr. Irving Zucker, performing research in the field of circadian rhythms, melatonin and torpor. Dr. Larkin received her Ph.D. in Biological Sciences from Stanford University in 1996, studying in the laboratory of Dr. H. Craig Heller. She received a M.S. degree in Zoology from University of Washington in 1991. She received her B.A. degree, cum laude with Honors in Biology, from Wellesley College in 1987.

Dr. Larkin has published a number of scholarly papers:

Hollingsworth JW, Whitehead G, Berman KG, Tekippe EM, Gilmour MI, Larkin JE, Quackenbush J, Schwartz DA.
Genetic basis of murine antibacterial defense to streptococcal lung infection.
Immunogenetics. 2007 Sep; 59(9): 713-24. Epub 2007 Aug 14. PMID: 17701033.

Jennie E Larkin, Bryan C Frank, Haralambos Gavras, Razvan Sultana & John Quackenbush.
Independence and reproducibility across microarray platforms.
Nature Methods. April 21, 2005; 10.1038/nmeth757: 337-44.

Jennie E Larkin, Bryan C Frank, Renee M Gaspard, Irena Duka, Haralambos Gavras, and John Quackenbush.
Cardiac transcriptional response to acute and chronic angiotensin II treatments.
Physiol. Genomics. May 4, 2004; 10.1152/physiolgenomics.00057.2004.

Larkin JE, T Yokogawa, P Franken and NF Ruby.
Homeostatic regulation of sleep in arrhythmic Siberian hamsters.
Am. J. Physiol. Regul. Integr. Comp. Physiol. February 12, 2004; 10.1152/ajpregu.00676.2003.

Bae, H, JE Larkin, I Zucker.
Juvenile Siberian hamsters display torpor and modified locomotor activity and body temperature rhythms in response to reduced food availability.
Physiol. Biochem. Zool. 2003 Nov-Dec; 76(6): 858-67.

Larkin JE, SM Yellon, and I Zucker.
Melatonin production accompanies arousal from daily torpor in Siberian hamsters.
Physiol. Biochem. Zool. 2003; 76(4): 577-85.

J. E. Larkin, P. Franken, and H. C. Heller
Loss of circadian organization of sleep and wakefulness during hibernation.
Am. J. Physiol. Regul. Integr. Comp. Physiol. April 1, 2002; 282(4): R1086 - 1095.

Freeman DA, JE Larkin, and L Seliby.
Testicular and somatic growth in Siberian hamsters depend on the melatonin-free interval between twice daily melatonin signals.
J. Neuroendocrinol. 2002 Mar; 14(3): 228-33.

Larkin JE, J Jones, and I Zucker.
Temperature-dependence of gonadal regression in Syrian hamsters exposed to short day lengths.
Am. J. Physiol. Regul. Integr. Comp. Physiol. 2002 Mar; 282(3): R744-R752.

Larkin, Jennie E. ; Freeman, David A. ; Zucker, Irving.
Low ambient temperature accelerates short-day responses in Siberian hamsters by altering responsiveness to melatonin.
Journal of Biological Rhythms. 2001; 16(1): 76-86.

Jennie E. Larkin, and H. Craig Heller.
Sleep after arousal from hibernation is not homeostatically regulated.
Am. J. Physiol. Regul. Integr. Comp. Physiol. 1999; 276: R522-R529.

Jennie E. Larkin and H. Craig Heller.
The Disappearing Slow Wave Activity of Hibernators.
Sleep Research Online. 1998; 1(2): 96-101.

Ganim, R.B., Peckol, E.L., Larkin, J., Ruchhoeft, M.L. and Cameron, J.S.
ATP-sensitive K+ channels in cardiac muscle from cold-acclimated goldfish: Characterization and altered response to ATP.
Comp. Biochem. Physiol. 1998; 119A:395-401.

Grahn, D. A., M. C. Heller, J. E. Larkin, and H. C. Heller.
Appropriate thermal manipulations eliminate tremors in rats recovering from halothane anesthesia.
J. Appl. Physiol. 1996; 81: 2565-2570.

Larkin, J. E., and H. C. Heller.
Temperature sensitivity of sleep homeostasis during hibernation in the golden-mantled ground squirrel (spermophilus lateralis).
Am. J. Physiol: Regul. Integr. Comp. Physiol. 1996 Apr; 270 (4 Pt 2): R777-84.

In her copious free time, Dr. Larkin and her dogs compete in agility and obedience events. Dr. Larkin was voted 2004 Canaan Dog Club of America Member Of The Year.